Sandro Sonnino Selected Research

Type A Niemann-Pick Disease

7/2022	Massive Accumulation of Sphingomyelin Affects the Lysosomal and Mitochondria Compartments and Promotes Apoptosis in Niemann-Pick Disease Type A.
9/2011	Secondary alterations of sphingolipid metabolism in lysosomal storage diseases.
3/2011	Brain pathology in Niemann Pick disease type A: insights from the acid sphingomyelinase knockout mice.
4/2009	Alterations of myelin-specific proteins and sphingolipids characterize the brains of acid sphingomyelinase-deficient mice, an animal model of Niemann-Pick disease type A.

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Sandro Sonnino Research Topics

Disease

12	Neoplasms (Cancer) 01/2018 - 09/2004
11	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2022 - 11/2005
9	Neuroblastoma 12/2020 - 01/2005
9	Carcinoma (Carcinomatosis) 10/2012 - 02/2003
5	Brain Diseases (Brain Disorder) 07/2022 - 06/2010
5	Parkinson Disease (Parkinson's Disease) 01/2020 - 06/2010
5	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 06/2010
4	Type A Niemann-Pick Disease 07/2022 - 04/2009
4	Cystic Fibrosis (Mucoviscidosis) 10/2020 - 10/2016
3	Niemann-Pick Diseases (Niemann Pick Disease) 07/2022 - 04/2009
3	Inflammation (Inflammations) 01/2017 - 01/2010
3	Guillain-Barre Syndrome 01/2017 - 03/2007
3	Ovarian Neoplasms (Ovarian Cancer) 11/2011 - 04/2006
2	Peripheral Nervous System Diseases (PNS Diseases) 02/2022 - 01/2017
2	Infections 01/2022 - 01/2014
2	Lung Diseases (Lung Disease) 10/2020 - 10/2016
2	Multiple Sclerosis 01/2020 - 02/2016
2	Sphingolipidoses (Sphingolipidosis) 01/2019 - 08/2014
2	Lysosomal Storage Diseases (Lysosomal Storage Disease) 01/2019 - 09/2011
2	GM2 Gangliosidoses (GM2 Gangliosidosis) 08/2014 - 06/2002
2	Sandhoff Disease (Sandhoff's Disease) 08/2014 - 11/2005
2	Gaucher Disease (Gaucher's Disease) 06/2014 - 11/2012
1	Gangliosidoses (Gangliosidosis) 01/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2020
1	Obesity 01/2020
1	Relapsing-Remitting Multiple Sclerosis 01/2019
1	Glioblastoma (Glioblastoma Multiforme) 01/2018
1	Prostatic Neoplasms (Prostate Cancer) 01/2018
1	Motor Neuron Disease (Primary Lateral Sclerosis) 01/2017
1	Pseudomonas Infections 01/2017
1	Pneumonia (Pneumonitis) 10/2016
1	Cholera 04/2016
1	Inborn Genetic Diseases (Disease, Hereditary) 08/2014
1	Nervous System Diseases (Neurological Disorders) 08/2014
1	Globoid Cell Leukodystrophy (Krabbe Disease) 11/2012

Drug/Important Bio-Agent (IBA)

17	SphingolipidsIBA 07/2022 - 02/2003
10	LipidsIBA 01/2020 - 08/2009
8	OligosaccharidesIBA 02/2022 - 01/2017
8	Proteins (Proteins, Gene)FDA Link 01/2021 - 09/2004
8	EnzymesIBA 01/2021 - 06/2002
7	GangliosidesIBA 02/2022 - 04/2006
6	G(M1) GangliosideIBA 02/2022 - 12/2017
6	CeramidesIBA 01/2019 - 04/2006
6	AcidsIBA 06/2014 - 04/2006
6	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 12/2012 - 04/2006
5	SphingomyelinsIBA 07/2022 - 04/2006
4	HydrolasesIBA 01/2021 - 01/2017
4	GlycosphingolipidsIBA 01/2017 - 01/2011
4	Caveolin 1IBA 11/2011 - 08/2007
4	FenretinideIBA 07/2010 - 02/2003
4	RetinoidsIBA 07/2010 - 09/2004
3	G(M3) GangliosideIBA 01/2020 - 08/2007
3	AntibodiesIBA 01/2017 - 03/2007
3	Neuraminidase (Sialidase)IBA 05/2015 - 02/2007
3	G(M2) Ganglioside (Ganglioside GM2)IBA 08/2014 - 11/2005
2	Polysaccharides (Glycans)IBA 01/2022 - 01/2017
2	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 10/2020 - 01/2017
2	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2019 - 01/2018
2	SphingosineIBA 01/2019 - 01/2005
2	sphingosine kinaseIBA 01/2018 - 06/2010
2	Hexosaminidases (Hexosaminidase)IBA 08/2014 - 11/2005
2	Glucosylceramidase (Glucocerebrosidase)IBA 06/2014 - 11/2012
2	GlucosidasesIBA 01/2014 - 12/2012
2	Liver X ReceptorsIBA 08/2013 - 01/2010
2	IntegrinsIBA 11/2011 - 03/2008
2	haematoside synthetaseIBA 11/2011 - 01/2010
2	neodymium pyrocatechin disulfonate (NPD)IBA 03/2011 - 04/2009
2	Amyloid beta-PeptidesIBA 09/2010 - 06/2010
2	4-oxofenretinideIBA 07/2010 - 09/2004
2	dihydroceramideIBA 07/2010 - 06/2010
1	CarbohydratesIBA 01/2022
1	AnionsIBA 06/2020
1	G(M1)-oligosaccharideIBA 01/2020
1	Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA 10/2019
1	Glucose (Dextrose)FDA LinkGeneric 01/2019
1	Galactose (Galactopyranose)FDA LinkGeneric 01/2019
1	Fingolimod Hydrochloride (FTY720)FDA Link 01/2019
1	trkA ReceptorIBA 01/2019
1	epidermal growth factor receptor VIIIIBA 01/2018
1	abirateroneIBA 01/2018
1	Macromolecular SubstancesIBA 01/2018
1	ErbB Receptors (EGF Receptor)IBA 01/2018
1	Neurofilament ProteinsIBA 12/2017
1	Bacterial ToxinsIBA 04/2016
1	Sulfoglycosphingolipids (Sulfatides)IBA 02/2016
1	Pyrimethamine (Daraprim)FDA Link 08/2014
1	CalciumIBA 06/2014
1	miglustat (Zavesca)FDA Link 01/2014
1	Messenger RNA (mRNA)IBA 01/2014
1	OxysterolsIBA 08/2013
1	GalactosidasesIBA 12/2012
1	GalactosylceramidaseIBA 11/2012
1	Glycoside Hydrolases (Endoglycosidases)IBA 11/2012
1	EpitopesIBA 03/2012
1	retinamideIBA 11/2011
1	SialyltransferasesIBA 11/2011
1	Peptides (Polypeptides)IBA 09/2010

Therapy/Procedure

4	Therapeutics 02/2022 - 08/2013
2	Radiotherapy 01/2018 - 10/2014
1	Investigational Therapies (Experimental Therapy) 06/2020